Will these bolt straight into my stock mounting points?

Yes. These are designed to use factory cab light locations with no drilling or structural modification. Swap the old housings for these and you're done.

Do I need to replace any wiring when I install these?

The LED bulbs plug into your existing harness, so no rewiring required. If your truck's cab light circuit is functional, these will work with it as-is.

Can I use these lights in place of work lights, or are they dome lights only?

These are cab dome lights designed for interior illumination. They're not rated for task lighting or exterior use; stick to factory cab light duty.